[Clinico-pathological correlation-Lebanese experience]

This is a retrospective and descriptive study done at an academic hospital center. It collects data about 143 patients admitted during 10 years at the hospital, between January 1989 and December 2000, to have renal biopsy for suspicion of glomerulopathy. The glomerulonephritides most frequently present were : mesangial proliferative glomerulonephritis [15%], membrano-proliferative glomerulonephritis [13%], chronic glomerulonephritis [13%], membranous glomerulonephritis [8%], proliferative focal and segmental glomerulonephritis [8%] and scleronodular focal glomerulonephritis [8%]. Pa-tients with arterial hypertension represented 89% of patients with chronic glomerulonephritis and 54% of patients with scleronodular focal glomerulonephritis. Those with heavy proteinuria represented 82? of patients with primarily membranous glomerulonephritis, 66% of patients with minimal change disease and 44% of patients with membrano-proliferalive glomerulonephritis. Those with active urinary sediment have had mostly membrano-proliferative glomerulonephritis, rapidly progressive glomerulonephritis, postinfectious glomerulonephritis and proliferative mesangial glomerulonephritis. High rates of evolution to end-stage renal disease, renal transplantation or dialysis were mostly depicted between patients with scleronodular focal glomerulonephritis [91% of cases], chronic [89% of cases] and ntembrano-proliferative [72% of cases] glomerulonephritis

[Pseudomyxoma peritoneal, about two cases and review of the literature]

In this article, we present two cases of peritoneal pseudomyxoma suspected on abdominal CT Scan and then confirmed on pathologic examination. A mucinus carcinoma was the primary lesion in the two cases, appendicular in the first case and with an undeterminate origin in the second. The prognosis was bad in these cases despite the debulking surgery and the systemic and intraperitoneal chemotherapy

Actinomycose vertebrale. A propos d'un cas et revue de la litterature

In this article, the case of a 32-year-old man with a paravertebral actinomycosis is discussed. Initially, the diagnosis was not obvious but it was confirmed later with the repetitive radiologic procedures, the elimination of other etiologies [purulent, mycobacterial or mycotic infections and neoplasia] and the biopsy Treatment with penicillin initially and then with tetracycline for a long term led to a very good outcome at a 3-year follow-up with a radiologic remission. Following the discussion of the case, a review of the literature concerning the paravertebral actinomycosis, its diagnostic clues and treatment is undertaken

Acute cocaine intoxication in a smuggler one case report and a review of the literature

The smuggling of cocaine into many countries by ingestion of wrapped cocaine packets and gastro-intestinal concealment is a common and well-recognized practice. This is a report of the case of a smuggler carrying 14 ingested packets of cocaine and who presented an acute intoxication with a rare complication, rhabdomyolysis, which were managed medically and the packets removed surgically. A discussion and a review of the literature are undertaken

Neonatal erythematous lupus and atrioventricular block A case with a review of the teratum bed

Neonatal lupus erythematosus is a rare syndrome. It is characterized by a transient lupus dermatitis and congenital heart block. The immunopathogenesis of the disease has been linked to the presence of the SSA antibody. In this report we describe a symptomatic congenital heart block in a year old male whose mother had documented systemic lupus erythematosus. We also discuss how to manage a woman with lupus erythematosus and positive antiSSA/Ro antibodies. We conclude that patients with neonatal lupus and their mothers shold be observed closely before delivery and for prolonged periods for signs of active disease

Les maladies inflammatoires des intestins et leurs manifestations extra-intestinales au Liban

101 cases classified as inflammatory bowel disease at the hotel dieu de france hospital between 1982 and 1994 were investigated. Files containing a sure diagnosis and complete clinical and biological investigations were included. 65 files were retained for the study: 48 cases had ulcerative colitis [UC], 17 had crohn's disease [CD]. UC averaged 4.7 admissions per 10.000 admissions to the hospital, while CD averaged 1.54 per 10.000. the UC/CD ratio was 2.8 and the female/male ratio was 1.4 for UC and 0.9 for CD. Medium follow-up was 6.4 years. 30% of our group was followed for more than 10 years. Overall frequency of extra intestinal manifestations was similar to that reported worldwide. This is especially true for UC. However, no cases of ankylosing spondylitis, sclerosing cholangitis or erythema nodosum were found. One case of pyoderma gangrenosum was found in the series of CD. Extraintestinal manifestations were found in 54% of UC patients and 94% of CD patients, probably because milder cases of this disease were misclassified as infectious diarrhea

Behcet's disease in Lebanon: reportof 100 cases

Purpose: To present clinical features of Behcet's disease in Lebanon and to evaluate the efficacy of treatment. Patients and methods: The 100 patients are seen at Hotel-Dieu de France Hospital of Beirut between 1980 and 1992. Diagnostic criteria are those of the Behcet Syndrome Research Committee of Japan. Results: Recurrent oral ulcers are present in 95% of cases, genital ulcers in 78%, ocular manifestations are more frequent than those of several studies whereas skin lesions and vascular signs are less frequent. Joint involvement are recorded in 65% of cases and neurological one in 14%. The effectiveness of colchicine therapy is confirmed for mucocutaneous lesions and arthritis. Immunosuppressive agents are more beneficial than steroids alone on serious uveitis. An aggressive treatment with corticosteroids and immunosuppressive drugs improve the prognosis of meningoencephalitis. Conclusion: Behcet's disease doesn't have any specific characteristics in Lebanon despite some variation in the frequency of lesions

manifestations digestives de la dermatomyositis juvenile: a propos d'un cas avec revue de la litterature

Childhood dermatomyositis should be separated from the adult polymyositis and is characterized by the frequency of vasculitis and ulcerations of the gastrointestinal tract. The authors present a case of colonic perforation with a review of the different disorders of the gastrointestinal system secondary to this disease